STAT2 Antikörper (AA 571-851)
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- Target Alle STAT2 Antikörper anzeigen
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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Bindungsspezifität
- AA 571-851
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAT2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Signal transducer and activator of transcription 2 protein (571-851AA)
- Isotyp
- IgG
- Top Product
- Discover our top product STAT2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Andere Bezeichnung
- STAT2 (STAT2 Produkte)
- Synonyme
- wu:fj84d07 antikoerper, p113 antikoerper, stat2 antikoerper, 1600010G07Rik antikoerper, AW496480 antikoerper, ISGF-3 antikoerper, P113 antikoerper, STAT113 antikoerper, signal transducer and activator of transcription 2 antikoerper, AGAP000099-PA antikoerper, stat2 antikoerper, STAT2 antikoerper, Stat2 antikoerper
- Hintergrund
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Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Aliases: Homo sapiens interferon alpha induced transcriptional activator antibody, interferon alpha induced transcriptional activator antibody, ISGF 3 antibody, ISGF3 antibody, MGC59816 antibody, P113 antibody, signal transducer and activator of transcription 2 113kD antibody, Signal transducer and activator of transcription 2 antibody, STAT113 antibody, Stat2 antibody, STAT2_HUMAN antibody
- UniProt
- P52630
- Pathways
- JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events
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