STAT2 Antikörper

Produktnummer ABIN6940668

Der Maus Monoklonal anti-STAT2 Antikörper (Klon STAT2-2650) (ABIN6940668) detektiert spezifisch STAT2 in IHC und StM. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für STAT2 Antikörper (ABIN6940668)

Target: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser STAT2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Klon: STAT2-2650

Produktdetails anti-STAT2 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human STAT2 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu STAT2

Target: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Andere Bezeichnung: STAT2

Hintergrund: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

Molekulargewicht: 113kDa

Gen-ID: 6773

UniProt: P52630

Pathways: JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events