Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Loss of wild-type Hras promotes the earliest stages of pancreatic tumorigenesis, and moreover results in more rapid progression of the disease. As such, mechanisms leading to activation of wild-type Ras proteins, including but not limited to redox-dependent reactions, may influence the development of pancreatic cancer.
High HRAS (zeige HRAS ELISA Kits) expression is associated with hepatocarcinogenesis.
p21-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 and ras(Ha)/ROCK2 (zeige ROCK2 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits) signalling in skin carcinogenesis.these data show that ROCK2 (zeige ROCK2 ELISA Kits) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 (zeige TP53 ELISA Kits) loss and novel NF-kappaB (zeige NFKB1 ELISA Kits) expression
this study shows that retinoic acid stabilizes HRas (zeige HRAS ELISA Kits) protein during neurogenesis.
we provide genetic evidence that the wild-type H-Ras and K-Ras proteins are bioequivalent in spite of their different structural and biological properties
loss of one allele of Hras (zeige HRAS ELISA Kits) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (zeige HRAS ELISA Kits) allele. However, loss of one or both alleles of Nras (zeige NRAS ELISA Kits) failed to alter tumor burden, either in the absence or presence of Hras (zeige HRAS ELISA Kits), after exposure to urethane.
H-ras (zeige HRAS ELISA Kits) isoform mediates protection against pressure overload-induced cardiac dysfunction in part through activation of AKT (zeige AKT1 ELISA Kits)/PI3K signaling pathway.
The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to de-repress c-Myc (zeige MYC ELISA Kits) expression and to promote cell transformation assisted by the constitutively active H-Ras (zeige HRAS ELISA Kits).
these contrasting signatures precisely match those proposed to confer bias toward Hras (zeige HRAS ELISA Kits)(CAA61CTA) versus Braf (zeige BRAF ELISA Kits)(GTG636GAG) mutations in the original tumor sets. Our findings highlight a novel mechanism whereby exposure history acts through strand-biased mutagenesis to specify activation of preferred oncogenes
The abnormal expression of epidermal cytokeratins suggests that Ha-Ras and Bcl-2 (zeige BCL2 ELISA Kits) suppress the terminal differentiation and sustain the stem cell-like features in epidermal keratinocytes
Suggest that loss of RASSF7 expression results in apoptosis in nucleus pulposus cells in human intervertebral disc degeneration.
truncated RASSF7 could act as an oncogene (zeige RAB1A ELISA Kits) in a small subset of tumours where it is mutated in this way.
The RASSF gene family members RASSF5 (zeige RASSF5 ELISA Kits), RASSF6 (zeige RASSF6 ELISA Kits) and RASSF7 show frequent DNA methylation (zeige HELLS ELISA Kits) in neuroblastoma (zeige ARHGEF16 ELISA Kits).
RASSF7 acts in concert with N-Ras (zeige NRAS ELISA Kits) to constitute a stress-sensitive temporary mechanism of apoptotic regulation.
RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B (zeige AURKB ELISA Kits) activation and chromosomal congression during mitosis.
"rare" alleles of HRas1 minisatellite are associated with increased risk of papillary thyroid cancer formation in children and adolescents after Chernobyl accident
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
, neuroblastoma ras oncogene
, transforming protein N-Ras
, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
, GTPase HRas
, transforming protein p21
, v-Ha-ras Harvey rat sarcoma viral oncogene-like protein
, H-ras 1 protein
, c-Ha-ras p21 protein
, c-Ha-ras transgene
, transforming protein P21
, HRAS1-related cluster protein 1
, HRAS1-related cluster-1
, Ras association (RalGDS/AF-6) domain family 7
, ras association domain-containing protein 7