anti-Rind (Kuh) Patched 2 Antikörper für Western Blotting
Recommended Patched 2 Antibody (geliefert von: Anmelden zum Anzeigen )
- Antigen
-
Patched 2 (PTCH2) Antikörper
Synonyme für dieses Antigen anzeigen- PTC2
- ptc2
- Ptch1
- ptc-2
- xptc-2
- xptch-2
- patched-2
- ptch2
- ptc-1
- ptc1
- ptch1
- patched 2
- patched 2 S homeolog
- patched 2 L homeolog
- PTCH2
- Ptch2
- ptch2.S
- ptch2.L
- ptch2
- Epitop
-
N-Term
Alternativen - Reaktivität
-
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
Alternativen - Wirt
-
Kaninchen
Alternativen - Klonalität
- Konjugat
-
Dieser Patched 2 Antikörper ist unkonjugiert
Alternativen - Applikation
-
Western Blotting (WB)
Alternativen - Optionen
- Hersteller
- Anmelden zum Anzeigen
- Hersteller Produkt- Nr.
- Anmelden zum Anzeigen
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Bilder
Produktnummer ABIN2782247
$ 289.00
Zzgl. Versandkosten $45.00
Zzgl. Versandkosten $45.00
| Relevance Score | ABIN | Application | Konjugat | Host | Isotype | Epitope | Hersteller | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN2627350 | IHC IHC (p) WB | Rabbit | IgG | AA 362-411 | Anmelden zum Anzeigen | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Patched 2 (PTCH2) Antikörper |
| Epitop | N-Term Alternativen |
| Reaktivität | Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus) Alternativen |
| Wirt | Kaninchen Alternativen |
| Klonalität | |
| Konjugat | Dieser Patched 2 Antikörper ist unkonjugiert Alternativen |
| Applikation |
Western Blotting (WB)
Alternativen
|
|
1 Publikation vorhanden |
| Hersteller | Anmelden zum Anzeigen |
Produktdetails anti-Patched 2 AntikörperTarget Details Patched 2 Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder |
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| Blocking Peptide | Zu diesem Produkt passt das Blocking Peptide ABIN982410. |
| Sequenz | LAQEALPENA SQQIHAFSST TLDDILHAFS EVSAARVVGG YLLMLAYACV |
| Homologie | Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93% |
| Produktmerkmale | This is a rabbit polyclonal antibody against PTCH2. It was validated on Western Blot using a cell lysate as a positive control. |
| Reinigung | Affinity Purified |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human PTCH2 |
| Plasmids, Primers & others | |
Target Details Patched 2Produktdetails anti-Patched 2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben |
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| Antigen | |
| Andere Bezeichnung | PTCH2 (PTCH2 Antibody Abstract) |
| Hintergrund |
PTCH2 is a member of the patched protein family. The patched protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. The gene encoding PTCH2 is shown to be mutated in a medulloblastoma and in a basal cell carcinoma, suggesting that it plays a role in the development of some tumors. This gene encodes a member of the patched gene family. The patched protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene is shown to be mutated in a medulloblastoma and in a basal cell carcinoma, suggesting that it plays a role in the development of some tumors. Alternative transcript variants have been described, but their biological function has not been determined. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 AF119569.1 1-10 11-534 AY359016.1 3-526 535-2066 AF087651.1 523-2054 2067-2509 AF119569.1 2067-2509 2510-2520 AF087651.1 2498-2508 2521-2700 AF119569.1 2521-2700 2701-3620 AY358555.1 2689-3608 3621-3624 AF087651.1 3609-3612 Alias Symbols: PTC2 Protein Interaction Partner: ARRB1, DHH, SMO, IHH, SHH, Protein Size: 1203 |
| Molekulargewicht | 130 kDa |
| Gen-ID | 8643 |
| NCBI Accession | NM_003738, NP_003729 |
| UniProt | Q9Y6C5 |
| Pathways | Hedgehog Signalweg |
AnwendungsinformationenProduktdetails anti-Patched 2 Antikörper Target Details Patched 2 Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben |
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| Applikations-hinweise | Optimal working dilutions should be determined experimentally by the investigator. |
| Kommentare |
Antigen size: 1203 AA |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
HandhabungProduktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Referenzen für anti-Patched 2 Antikörper (ABIN2782247) Bilder zurück nach oben |
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| Format | Liquid |
| Konzentration | Lot specific |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose. |
| Konservierungs-mittel | Sodium azide |
| Vorsichtsmaßnahmen | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Handhabung | Avoid repeated freeze-thaw cycles. |
| Lagerung | -20 °C |
| Informationen zur Lagerung | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Referenzen für anti-Patched 2 Antikörper (ABIN2782247)Produktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Handhabung Bilder zurück nach oben |
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| Allgemeine Veröffentlichungen |
Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: "The DNA sequence and biological annotation of human chromosome 1. ..." in: Nature, Vol. 441, Issue 7091, pp. 315-21, 2006 |
BilderProduktdetails anti-Patched 2 Antikörper Target Details Patched 2 Anwendungsinformationen Handhabung Referenzen für anti-Patched 2 Antikörper (ABIN2782247) zurück nach oben |
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| Bilder des Herstellers |
WB Suggested Anti-PTCH2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Pos...
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