anti-Human CCR5 Antikörper für Immunofluorescence

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • C-C motif chemokine receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • C-C motif chemokine receptor 5
  • CCR5
  • Ccr5
Reaktivität
Human
468
79
65
14
14
3
2
1
1
1
1
1
Wirt
Maus
223
182
71
14
13
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist unkonjugiert
43
27
20
19
19
16
14
13
9
9
9
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF)
297
207
137
64
61
57
56
33
29
18
14
12
8
8
6
5
4
4
3
2
2
2
2
2
1
1
1
Optionen
Hersteller
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Produktnummer ABIN2689054
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN372756 EIA IF IHC (p) WB Goat IgG AA 3-30, C-Term Anmelden zum Anzeigen Polyclonal 2
1 ABIN151963 Func ICC FACS IF in vitro ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal 2
1 ABIN205374 FACS IF ELISA Mouse IgG1 Anmelden zum Anzeigen T21-8 0
1 ABIN180777 EIA IF WB Mouse IgG1 C-Term, pSer349 Anmelden zum Anzeigen E11-19 2
1 ABIN180776 EIA IF WB Mouse IgG2b C-Term, pSer337 Anmelden zum Anzeigen V14-2 0
1 ABIN180775 EIA IF WB Mouse IgG1 C-Term, Ser337 Anmelden zum Anzeigen R-C10 0
1 ABIN205529 FACS IF ELISA WB Mouse IgG2b Phosphopeptide Anmelden zum Anzeigen V14-2 0
1 ABIN4289123 FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1 0
1 ABIN4289122 FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1 0
1 ABIN4289121 FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1 0
1 ABIN265738 ICC FACS IF Mouse IgG2b Anmelden zum Anzeigen 45523111 0
1 ABIN206542 FACS IF ELISA WB Mouse IgG2b pSer337 Anmelden zum Anzeigen 0
1 ABIN206543 FACS IF ELISA WB Mouse IgG1 pSer349 Anmelden zum Anzeigen 0
1 ABIN2221613 FACS IF ELISA WB Mouse IgG2b pSer337 Anmelden zum Anzeigen 10B944 0
1 ABIN2221612 FACS IF ELISA WB Mouse IgG1 C-Term Anmelden zum Anzeigen 10B940 0
1 ABIN2221608 FACS IF ELISA WB Mouse IgG1 pSer349 Anmelden zum Anzeigen 10B945 0
1 ABIN4289124 CyTOF FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1 0
1 ABIN4289125 CyTOF FACS IF IHC (fro) Mouse IgG2a kappa N-Term Anmelden zum Anzeigen 12D1 0
1 ABIN2221632 FACS IF IHC Rat IgG2a Anmelden zum Anzeigen HEK-1-85a 0
1 ABIN4289151 FACS ICC IF DyLight 650 Mouse IgG2b Anmelden zum Anzeigen 45523111 0

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Human
(468), (79), (65), (14), (14), (3), (2), (1), (1), (1), (1), (1)
Wirt Maus
(223), (182), (71), (14), (13)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist unkonjugiert
(43), (27), (20), (19), (19), (16), (14), (13), (9), (9), (9), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Flow Cytometry (FACS), Immunofluorescence (IF)
(297), (207), (137), (64), (61), (57), (56), (33), (29), (18), (14), (12), (8), (8), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2689054) Bilder
Marke BD Pharmingen™
Produktmerkmale The 2D7/CCR5 monoclonal antibody specifically binds to the human chemokine receptor, CCR5. CCR5 is also known as CD195. CCR5 is a seven transmembrane-spanning G protein-associated molecule. CCR5 belongs to the beta chemokine receptor family. It is expressed on a subset of T lymphocytes (CD3+CD45RO+CD95+). CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1), and monocyte chemoattractant protein 2 (MCP-2). Additionally, CCR5 has been found to be a co-receptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission. Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection. This antibody has been shown to block ligand and gp120 binding. It is also able to neutralize HIV infection. Profile of peripheral blood lymphocytes analyzed by flow cytomery.

BD Pharmingen™ Purified Mouse Anti-Human CD195 - Purified - Clone 2D7/CCR5 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Klon 2D7-CCR5
Isotyp IgG2a, kappa

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2689054) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 (CCR5 Antibody Abstract)
Hintergrund Synonyms: CCR5, C-C chemokine receptor type 5, CC-CKR-5, CKR5, CHEMR13 Entrez Gene ID: 1234
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2689054) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN2689054) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 4°C.

Referenzen für anti-CCR5 Antikörper (ABIN2689054)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Hancock: "Chemokines and the pathogenesis of T cell-dependent immune responses." in: The American journal of pathology, Vol. 148, Issue 3, pp. 681-4, 1997

Wu, Paxton, Kassam, Ruffing, Rottman, Sullivan, Choe, Sodroski, Newman, Koup, Mackay: "CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro." in: The Journal of experimental medicine, Vol. 185, Issue 9, pp. 1681-91, 1997

Choe, Farzan, Sun, Sullivan, Rollins, Ponath, Wu, Mackay, LaRosa, Newman, Gerard, Gerard, Sodroski: "The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates." in: Cell, Vol. 85, Issue 7, pp. 1135-48, 1996

Deng, Liu, Ellmeier, Choe, Unutmaz, Burkhart, Di Marzio, Marmon, Sutton, Hill, Davis, Peiper, Schall, Littman, Landau: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996

Doranz, Rucker, Yi, Smyth, Samson, Peiper, Parmentier, Collman, Doms: "A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors." in: Cell, Vol. 85, Issue 7, pp. 1149-58, 1996

Dragic, Litwin, Allaway, Martin, Huang, Nagashima, Cayanan, Maddon, Koup, Moore, Paxton: "HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5." in: Nature, Vol. 381, Issue 6584, pp. 667-73, 1996

Raport, Gosling, Schweickart, Gray, Charo: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996