CCR5 Antikörper (AA 201-300)

Produktnummer ABIN741375

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-CCR5 Antikörper (ABIN741375) detektiert spezifisch CCR5 in WB, FACS, IHC (p), IHC (fro), IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CCR5 Antikörper (AA 201-300) (ABIN741375)

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CCR5 Antikörper

Bindungsspezifität: AA 201-300

Verwendungszweck: CCR5 Polyclonal Antibody

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCR-5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CCR5 Antikörper (ABIN741375)

Ochoa-Callejero, Pérez-Martínez, Rubio-Mediavilla, Oteo, Martínez, Blanco: "Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model." in: PLoS ONE, Vol. 8, Issue 1, pp. e53992, (2013) (PubMed).

Details zu CCR5

Target: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Andere Bezeichnung: CCR5/CD195

Hintergrund:

Synonyms: CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, C-C chemokine receptor type 5, C-C CKR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor

Background: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Gen-ID: 1234

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size