anti-Human CCR5 Antikörper für Intracellular Flow Cytometry

Recommended CCR5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
C-C Chemokine Receptor Type 5 (CCR5) Antikörper
  • CC-CKR-5
  • CCCKR5
  • CCR-5
  • CD195
  • CKR-5
  • CKR5
  • CMKBR5
  • IDDM22
  • Ckr5
  • Cmkbr5
  • CCR1-L
  • GPCR
  • CCR5
  • AM4-7
  • C-C motif chemokine receptor 5 (gene/pseudogene)
  • chemokine (C-C motif) receptor 5
  • C-C motif chemokine receptor 5
  • CCR5
  • Ccr5
Reaktivität
Human
459
80
66
14
13
3
2
1
1
1
1
1
Wirt
Ratte
222
178
66
15
13
Klonalität
Monoklonal
Konjugat
Dieser CCR5 Antikörper ist konjugiert mit FITC
42
25
20
19
19
16
13
13
9
9
9
6
5
5
5
5
4
4
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Intracellular Flow Cytometry (ICFC)
292
205
130
72
62
56
55
33
29
18
14
12
8
7
6
5
4
4
3
2
2
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2661552
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2663124 FACS ICFC PE Mouse IgG1 kappa Anmelden zum Anzeigen T21-8 6
1 ABIN2663125 FACS ICFC PE Mouse IgG1 kappa Anmelden zum Anzeigen T21-8 6
1 ABIN2661375 FACS ICFC FITC Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1
1 ABIN2661376 FACS ICFC FITC Mouse IgG2b kappa Anmelden zum Anzeigen J418F1 1

General

Antigen C-C Chemokine Receptor Type 5 (CCR5) Antikörper
Reaktivität Human
(459), (80), (66), (14), (13), (3), (2), (1), (1), (1), (1), (1)
Wirt Ratte
(222), (178), (66), (15), (13)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CCR5 Antikörper ist konjugiert mit FITC
(42), (25), (20), (19), (19), (16), (13), (13), (9), (9), (9), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Applikation Intracellular Flow Cytometry (ICFC)
(292), (205), (130), (72), (62), (56), (55), (33), (29), (18), (14), (12), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Pubmed 11 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-CCR5 Antikörper

Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2661552) Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Klon HEK-1-85a
Isotyp IgG2a kappa

Target Details CCR5

Produktdetails anti-CCR5 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2661552) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD195 (CCR5 Antibody Abstract)
Hintergrund CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Pathways Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size

Anwendungsinformationen

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2661552) Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Referenzen für anti-CCR5 Antikörper (ABIN2661552) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CCR5 Antikörper (ABIN2661552)

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Liu, Dominska-Ngowe, Dykxhoorn: "Target silencing of components of the conserved oligomeric Golgi complex impairs HIV-1 replication." in: Virus research, Vol. 192, pp. 92-102, 2014

Osman, Bhuyan, Hashimoto, Nasser, Maekawa, Suzu: "M-CSF inhibits anti-HIV-1 activity of IL-32, but they enhance M2-like phenotypes of macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5083-9, 2014

Al-ofi, Coffelt, Anumba: "Monocyte subpopulations from pre-eclamptic patients are abnormally skewed and exhibit exaggerated responses to Toll-like receptor ligands." in: PLoS ONE, Vol. 7, Issue 7, pp. e42217, 2012

Vaday, Peehl, Kadam, Lawrence: "Expression of CCL5 (RANTES) and CCR5 in prostate cancer." in: The Prostate, Vol. 66, Issue 2, pp. 124-34, 2005

Lai, Yang, Douglas, Wang, Riedel, Ho: "Quantification of CCR5 mRNA in human lymphocytes and macrophages by real-time reverse transcriptase PCR assay." in: Clinical and diagnostic laboratory immunology, Vol. 10, Issue 6, pp. 1123-8, 2003

Mañes, Mira, Colomer, Montero, Real, Gómez-Moutón, Jiménez-Baranda, Garzón, Lacalle, Harshman, Ruíz, Martínez-A: "CCR5 expression influences the progression of human breast cancer in a p53-dependent manner." in: The Journal of experimental medicine, Vol. 198, Issue 9, pp. 1381-9, 2003

Mueller, Kelly, Strange: "Pathways for internalization and recycling of the chemokine receptor CCR5." in: Blood, Vol. 99, Issue 3, pp. 785-91, 2002

Combadiere, Ahuja, Tiffany, Murphy: "Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES." in: Journal of leukocyte biology, Vol. 60, Issue 1, pp. 147-52, 1996

Deng, Liu, Ellmeier, Choe, Unutmaz, Burkhart, Di Marzio, Marmon, Sutton, Hill, Davis, Peiper, Schall, Littman, Landau: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996

Samson, Labbe, Mollereau, Vassart, Parmentier: "Molecular cloning and functional expression of a new human CC-chemokine receptor gene." in: Biochemistry, Vol. 35, Issue 11, pp. 3362-7, 1996

Raport, Gosling, Schweickart, Gray, Charo: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996

Bilder

Produktdetails anti-CCR5 Antikörper Target Details CCR5 Anwendungsinformationen Handhabung Referenzen für anti-CCR5 Antikörper (ABIN2661552) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (FITC) (ABIN2661552) anti-C-C Chemokine Receptor Type 5 (CCR5) antibody (FITC)