IKK alpha Antikörper
Kurzübersicht für IKK alpha Antikörper (ABIN969056)
Target
Alle IKK alpha (CHUK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- CHUK Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human CHUK expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling." in: Molecular cancer, Vol. 9, pp. 283, (2010) (PubMed).
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: "Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling." in: Molecular cancer, Vol. 9, pp. 283, (2010) (PubMed).
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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Andere Bezeichnung
- CHUK
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Hintergrund
- This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
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Molekulargewicht
- 85 kDa
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Gen-ID
- 1147
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UniProt
- O15111
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Pathways
- PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
Target
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