VEGFR2 (Ab-1175) antibody detects endogenous levels of total VEGFR2 protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human VEGFR2 around the phosphorylation site of tyrosine 1175 (K-D-YP-I-V).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Lamalice, Houle, Jourdan, Huot: "Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38." in: Oncogene, Vol. 23, Issue 2, pp. 434-45, (2004) (PubMed).
Takahashi, Yamaguchi, Chida, Shibuya: "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells." in: The EMBO journal, Vol. 20, Issue 11, pp. 2768-78, (2001) (PubMed).