IKK alpha Antikörper (AA 500-590)
(2 Referenzen)Kurzübersicht für IKK alpha Antikörper (AA 500-590) (ABIN965896)
Target
Alle IKK alpha (CHUK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 500-590
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of CHUK (aa500-590) expressed in E. Coli.
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Isotyp
- IgG1
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anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (C-Term) antibody
CHUK Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pSer176), (pSer177) antibodyCHUK Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4B8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK Reaktivität: Human WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 3G12H9 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 646-745) antibodyCHUK Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 1F8 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 411-745) antibodyCHUK Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (pThr23) antibodyCHUK Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) antibodyCHUK Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB2159 unconjugated
anti-conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (AA 553-582), (C-Term) antibodyCHUK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41164 unconjugated
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Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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: "Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation." in: Molecular cell, Vol. 18, Issue 1, pp. 71-82, (2005) (PubMed).
: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).
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: "Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation." in: Molecular cell, Vol. 18, Issue 1, pp. 71-82, (2005) (PubMed).
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- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
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Andere Bezeichnung
- CHUK
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Hintergrund
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CHUK: conserved helix-loop-helix ubiquitous kinase. This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Synonyms: IKK1, IKKA, IKBKA -
Gen-ID
- 1147
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Pathways
- PI3K-Akt Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
Target
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