F12 Antikörper

Produktnummer ABIN957858

Produktdetails anti-F12 Antikörper

Target: F12 (Coagulation Factor XII (F12))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser F12 Antikörper ist unkonjugiert

Applikation: Immunodiffusion (ID)

Spezifität: Human F12 / Factor XII. The defined antibody reactivity is restricted to FXII, FXIIa and complexes of FXIIa with other proteins. In immunoelectrophoresis, bi-dimensional electrophoresis and radial immunodiffusion (Ouchterlony) against normal plasma, a single precipitin line is obtained which shows a reaction of identity with precipitated purified Factor XII. No reaction is obtained with FXII-depleted plasma. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in immunoelectrophoresis a reaction with Rhesus monkey plasma has been found.

Aufreinigung: Immunoaffinity absorbed

Immunogen: Human Factor XII

Type of Immunogen: Purified protein

Anwendungsinformationen

Applikationshinweise: Approved: ID

Usage: This antiserum is primarily intended for the measurement of Factor XII in human plasma using the EID-method (Laurell): a specially purified agarose solution containing between 1 and 2 % antiserum is poured onto a glass plate and allowed to gel. Plasma containing FXII is incorporated into a series of wells and electrophoresis is performed. Rockets due to antigen/antibody reaction are measured. The height of the rocket is directly proportional to the FXII concentration in the plasma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile distilled water 1 ml

Konzentration: Lot specific

Buffer: Lyophilized antiserum

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C
Short term: +4°C. Avoid repeat freeze-thaw cycles.

Details zu F12

Target: F12 (Coagulation Factor XII (F12))

Andere Bezeichnung: F12 / Factor XII (F12 Produkte)

Synonyme: HAE3 antikoerper, HAEX antikoerper, HAF antikoerper, FXII antikoerper, coagulation factor XII antikoerper, coagulation factor XII (Hageman factor) antikoerper, F12 antikoerper

Hintergrund: Name/Gene ID: F12
Subfamily: Serine S1
Family: Protease

Synonyms: F12, Beta-factor XIIa part 2, Beta-factor XIIa part 1, Coagulation factor XII, F12 deficiency, Factor XII, Factor XII deficiency, HAE3, HAEX, Hageman factor, HAF

Gen-ID: 2161

UniProt: P00748

Pathways: Komplementsystem