NSUN2 Antikörper (Middle Region)
-
- Target Alle NSUN2 Antikörper anzeigen
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
-
Bindungsspezifität
- AA 426-455, Middle Region
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser NSUN2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody reacts to NSUN2.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human and Mouse.
- Aufreinigung
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 426-455 amino acids from the Central region of human NSUN2
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NSUN2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Andere Bezeichnung
- NSUN2 (NSUN2 Produkte)
- Synonyme
- D13Wsu123e antikoerper, Misu antikoerper, MISU antikoerper, MRT5 antikoerper, SAKI antikoerper, TRM4 antikoerper, RGD1311954 antikoerper, NOL1/NOP2/Sun domain family member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 antikoerper, NOP2/Sun RNA methyltransferase family, member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 S homeolog antikoerper, Nsun2 antikoerper, NSUN2 antikoerper, nsun2.S antikoerper
- Hintergrund
- Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA) (Brzezicha et al., 2006 [PubMed 17071714])Synonyms: NOL1/NOP2/Sun domain family member 2, SAKI, Substrate of AIM1/Aurora kinase B, TRM4, tRNA (cytosine-5-)-methyltransferase, tRNA (cytosine-5-)-methyltransferase NSUN2, tRNA methyltransferase 4 homolog
- Molekulargewicht
- 86471 Da
- Gen-ID
- 54888
- NCBI Accession
- NP_001180384
-