NSUN2 Antikörper (Internal Region)

Produktnummer ABIN6263746

Produktdetails anti-NSUN2 Antikörper

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSUN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: NSUN2 Antibody detects endogenous levels of total NSUN2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NSUN2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NSUN2

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Andere Bezeichnung: NSUN2 (NSUN2 Produkte)

Synonyme: D13Wsu123e antikoerper, Misu antikoerper, MISU antikoerper, MRT5 antikoerper, SAKI antikoerper, TRM4 antikoerper, RGD1311954 antikoerper, NOL1/NOP2/Sun domain family member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 antikoerper, NOP2/Sun RNA methyltransferase family, member 2 antikoerper, NOP2/Sun RNA methyltransferase family member 2 S homeolog antikoerper, Nsun2 antikoerper, NSUN2 antikoerper, nsun2.S antikoerper

Hintergrund:

Description: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

Gene: NSUN2

Molekulargewicht: 90-100 kDa

Gen-ID: 54888

UniProt: Q08J23