GUCY2D Antikörper (Middle Region)

Produktnummer ABIN952663

Produktdetails anti-GUCY2D Antikörper

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Bindungsspezifität: AA 547-578, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human GUCY2D / RETGC1 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 547-578 amino acids from the Central region of human GUCY2D / RETGC1

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GUCY2D

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Andere Bezeichnung: GUCY2D / RETGC1 (GUCY2D Produkte)

Synonyme: GUCY2D antikoerper, CORD5 antikoerper, CORD6 antikoerper, CYGD antikoerper, GUC1A4 antikoerper, GUC2D antikoerper, LCA antikoerper, LCA1 antikoerper, RCD2 antikoerper, RETGC-1 antikoerper, ROS-GC1 antikoerper, ROSGC antikoerper, retGC antikoerper, guanylate cyclase 2D, retinal antikoerper, guanylate cyclase 2d antikoerper, GUCY2D antikoerper, Gucy2d antikoerper

Hintergrund: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].Synonyms: CORD6, GUC1A4, GUC2D, PGCD, RETGC, RETGC-1, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase, retinal Guanylate cyclase 2D

Molekulargewicht: 120059 Da

Gen-ID: 3000

NCBI Accession: NP_000171

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction