GUCY2D Antikörper (AA 540-570)

Produktnummer ABIN655516

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GUCY2D in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für GUCY2D Antikörper (AA 540-570) (ABIN655516)

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB19346

Produktdetails anti-GUCY2D Antikörper

Bindungsspezifität: AA 540-570

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GUCY2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 540-570 amino acids from the Central region of human GUCY2D.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu GUCY2D

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Andere Bezeichnung: GUCY2D

Hintergrund: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].

Molekulargewicht: 120059

Gen-ID: 3000

NCBI Accession: NP_000171

UniProt: Q02846

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction