GUCY2D Antikörper (AA 52-350)

Produktnummer ABIN1680144

Der Kaninchen Polyklonal anti-GUCY2D Antikörper (ABIN1680144) detektiert spezifisch GUCY2D in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GUCY2D Antikörper (AA 52-350) (ABIN1680144)

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GUCY2D Antikörper

Bindungsspezifität: AA 52-350

Sequenz: AVFTVGVLGP WACDPIFSRA RPDLAARLAA ARLNRDPGLA GGPRFEVALL PEPCRTPGSL GAVSSALARV SGLVGPVNPA ACRPAELLAE EAGIALVPWG CPWTQAEGTT APAVTPAADA LYALLRAFGW ARVALVTAPQ DLWVEAGRSL STALRARGLP VASVTSMEPL DLSGAREALR KVRDGPRVTA VIMVMHSVLL GGEEQRYLLE AAEELGLTDG SLVFLPFDTI HYALSPGPEA LAALANSSQL RRAHDAVLTL TRHCPSEGSV LDSLRRAQER RELPSDLNLQ QVSPLFGTI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GUCY2D

Target: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Andere Bezeichnung: GUCY2D

Hintergrund: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.,GUCY2D,CORD5,CORD6,CYGD,GUC1A4,GUC2D,LCA,LCA1,RCD2,RETGC-1,ROS-GC1,ROSGC,retGC,Signal Transduction,Neuroscience,GUCY2D

Molekulargewicht: 120 kDa

Gen-ID: 3000

UniProt: Q02846

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction