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DFFB Antikörper (N-Term)
DFFB
Reaktivität: Human
WB, FACS, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-DFFB Antikörper
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Target
Alle DFFB Antikörper anzeigen
DFFB
(DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
Bindungsspezifität
Alle Epitope für DFFB Antikörper
AA 1-30, N-Term
Reaktivität
Alle Reaktivitäten für DFFB Antikörper
Human
Wirt
Alle Wirte für DFFB Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DFFB Antikörper
Polyklonal
Konjugat
Alle Konjugate für DFFB Antikörper
Dieser DFFB Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DFFB Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody recognizes Human DFFB / CAD (N-term).
Aufreinigung
Affinity Chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Human DFFB / CAD. Genename: DFFB
Isotyp
Ig Fraction
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Discover our top product DFFB Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS, 0.09 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu DFFB
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Target
DFFB
(DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
Andere Bezeichnung
DFFB / CAD (DFFB Produkte )
Synonyme
CAD antikoerper, CPAN antikoerper, DFF-40 antikoerper, DFF2 antikoerper, DFF40 antikoerper, LOC100223514 antikoerper, 40kDa antikoerper, 5730477D02Rik antikoerper, Didff antikoerper, Cad antikoerper, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antikoerper, DNA fragmentation factor subunit beta antikoerper, DNA fragmentation factor, beta polypeptide (caspase-activated DNase) antikoerper, DNA fragmentation factor, beta subunit antikoerper, CAD antikoerper, DFFB antikoerper, dffb antikoerper, LOC100223514 antikoerper, Dffb antikoerper
Hintergrund
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosisSynonyms: CPAN, Caspase-activated DNase, Caspase-activated deoxyribonuclease, Caspase-activated nuclease, DFF-40, DFF2, DFF40, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor subunit beta
Molekulargewicht
39110 Da
Gen-ID
1677
NCBI Accession
NP_004393
Pathways
Apoptose , Caspase Kaskade in der Apoptose
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