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CD22 Antikörper (C-Term)

CD22 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN929370
  • Target Alle CD22 Antikörper anzeigen
    CD22 (CD22 Molecule (CD22))
    Bindungsspezifität
    • 16
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 153
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 101
    • 61
    • 14
    Kaninchen
    Klonalität
    • 124
    • 54
    Polyklonal
    Konjugat
    • 81
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD22 Antikörper ist unkonjugiert
    Applikation
    • 111
    • 71
    • 45
    • 38
    • 38
    • 18
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    CD22 antibody was raised in rabbit using the C terminal of CD22 as the immunogen
    Top Product
    Discover our top product CD22 Primärantikörper
  • Applikationshinweise
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Kommentare

    CD22 Blocking Peptide, catalog no. 33R-10236, is also available for use as a blocking control in assays to test for specificity of this CD22 antibody

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    CD22 (CD22 Molecule (CD22))
    Andere Bezeichnung
    CD22 (CD22 Produkte)
    Synonyme
    A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
    Hintergrund
    CD22 mediates B-cell B-cell interactions. CD22 may be involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins, one of which is CD45. CD22 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response CD22 seems to be involved in regulation of B-cell antigen receptor signaling. CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Synonyms: Polyclonal CD22 antibody, Anti-CD22 antibody, CD22 molecule antibody, FLJ22814 antibody, MGC130020 antibody, SIGLEC-2 antibody, SIGLEC2 antibody.
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