CD22 Antikörper (AA 708-847)
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- Target Alle CD22 Antikörper anzeigen
- CD22 (CD22 Molecule (CD22))
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Bindungsspezifität
- AA 708-847
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD22 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- LQRRWKRTQS QQGLQENSSG QSFFVRNKKV RRAPLSEGPH SLGCYNPMME DGISYTTLRF PEMNIPRTGD AESSEMQRPP PDCDDTVTYS ALHKRQVGDY ENVIPDFPED EGIHYSELIQ FGVGERPQAQ ENVDYVILKH
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 708-847 of human CD22 (NP_001762.2).
- Isotyp
- IgG
- Top Product
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
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anti-CD22 Molecule (CD22) (AA 696-724), (C-Term) antibodyCD22 Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:10 - 1:100
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD22 (CD22 Molecule (CD22))
- Andere Bezeichnung
- CD22 (CD22 Produkte)
- Synonyme
- A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
- Hintergrund
- Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Human Siglec-2, also known as B-cell antigen CD22 or Blymphocyte cell adhesion molecule (BL-CAM), is a B-cell restricted glycoprotein that is expressed in the cytoplasm of progenitor B and pre-B cells and on the surface of mature B cells. Two distinct human Siglec2/CD22 cDNAs that arise from differential RNA processing of the same gene have been isolated. Siglec2/CD22 is an adhesion molecule that preferentially binds alpha 2,6- linked sialic acid on the same (cis) or adjacent (trans) cells. Interaction of CD22 with trans ligands on opposing cells was found to be favored over the binding of ligands in cis.,CD22,SIGLEC-2,SIGLEC2,Cancer,Tumor immunology,Tumor-associated antigens,Tumor biomarkers,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,CD22
- Molekulargewicht
- 75 kDa/84 kDa/85 kDa/95 kDa
- Gen-ID
- 933
- UniProt
- P20273
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