TLR10 Antikörper (Internal Region)

Produktnummer ABIN920630

Produktdetails anti-TLR10 Antikörper

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Positive Control: Highly expressed in spleen, lymph node, thymus, tonsil, and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

Aufreinigung: Antigen Immunoaffinity purified

Immunogen: Rabbit polyclonal TLR10 antibody was raised against a peptide corresponding to 14 amino acids near the middle of human TLR10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: use at 0.5-1 µg/mL. Despite its predicted size of ~90 kDa, a band corresponding to TLR10 is observed at ~75 kDa in immunoblot assays.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TLR10

Target: TLR10 (Toll-Like Receptor 10 (TLR10))

Abstract: TLR10 Produkte

Synonyme: TLR10 antikoerper, CD290 antikoerper, toll like receptor 10 antikoerper, toll-like receptor 10 antikoerper, TLR10 antikoerper, Tlr10 antikoerper

Hintergrund: Toll-like receptors (TRLs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These products act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is highly homologous to TLRs 1, and 6, and is most highly expressed in lymphoid tissues. Most recently genetic variation in TLR10 has been associated with contributing to asthma risk. It should be noted that TLR10 exists in mice only as a pseudogene. Synonyms:

Molekulargewicht: 94.5 kDa

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades