WISP1 Antikörper (AA 237-295) (Alexa Fluor 555)

Produktnummer ABIN920001

Produktdetails anti-WISP1 Antikörper (Alexa Fluor 555)

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Bindungsspezifität: AA 237-295

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP1 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WISP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu WISP1

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Andere Bezeichnung: WISP1 (WISP1 Produkte)

Synonyme: CCN4 antikoerper, WISP1c antikoerper, WISP1i antikoerper, WISP1tc antikoerper, WISP-1 antikoerper, WISP1 antikoerper, si:ch211-38f10.2 antikoerper, AW146261 antikoerper, Elm1 antikoerper, zgc:172276 antikoerper, WNT1 inducible signaling pathway protein 1 antikoerper, WNT1 inducible signaling pathway protein 1a antikoerper, WNT1-inducible-signaling pathway protein 1-like antikoerper, WNT1 inducible signaling pathway protein 1b antikoerper, WISP1 antikoerper, wisp1a antikoerper, Wisp1 antikoerper, LOC100627044 antikoerper, wisp1b antikoerper

Hintergrund:

Synonyms: CCN4, WISP1c, WISP1i, WISP1tc, WNT1-inducible-signaling pathway protein 1, WISP-1, CCN family member 4, Wnt-1-induced secreted protein, WISP1

Background: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Gen-ID: 8840

UniProt: O95388

Pathways: WNT Signalweg, Growth Factor Binding