WISP1 Antikörper (C-Term)

Produktnummer ABIN6266028

Produktdetails anti-WISP1 Antikörper

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WISP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: WISP1 Antibody detects endogenous levels of total WISP1.

Homologie: Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WISP1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu WISP1

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Andere Bezeichnung: WISP1 (WISP1 Produkte)

Synonyme: CCN4 antikoerper, WISP1c antikoerper, WISP1i antikoerper, WISP1tc antikoerper, WISP-1 antikoerper, WISP1 antikoerper, si:ch211-38f10.2 antikoerper, AW146261 antikoerper, Elm1 antikoerper, zgc:172276 antikoerper, WNT1 inducible signaling pathway protein 1 antikoerper, WNT1 inducible signaling pathway protein 1a antikoerper, WNT1-inducible-signaling pathway protein 1-like antikoerper, WNT1 inducible signaling pathway protein 1b antikoerper, WISP1 antikoerper, wisp1a antikoerper, Wisp1 antikoerper, LOC100627044 antikoerper, wisp1b antikoerper

Hintergrund:

Description: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Gene: WISP1

Molekulargewicht: 40 kDa

Gen-ID: 8840

UniProt: O95388

Pathways: WNT Signalweg, Growth Factor Binding