TIRAP Antikörper (AA 81-221) (Cy5.5)

Produktnummer ABIN917815

Produktdetails anti-TIRAP Antikörper (Cy5.5)

Target: TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))

Bindungsspezifität: AA 81-221

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIRAP Antikörper ist konjugiert mit Cy5.5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIRAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TIRAP

Target: TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))

Andere Bezeichnung: TIRAP (TIRAP Produkte)

Synonyme: mal antikoerper, wyatt antikoerper, BACTS1 antikoerper, Mal antikoerper, MyD88-2 antikoerper, AA407980 antikoerper, C130027E04Rik antikoerper, Tlr4ap antikoerper, Wyatt antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antikoerper, TIR domain containing adaptor protein antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antikoerper, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antikoerper, tirap antikoerper, TIRAP antikoerper, tirap.L antikoerper, Tirap antikoerper

Hintergrund:

Synonyms: Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIRAP, MAL

Background: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Gen-ID: 114609

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades