NOL3 Antikörper (AA 1-100) (Cy3)

Produktnummer ABIN909162

Produktdetails anti-NOL3 Antikörper (Cy3)

Target: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Bindungsspezifität: AA 1-100

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOL3 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Nucleolar protein 3/Apoptosis repressor with CARD

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NOL3

Target: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Andere Bezeichnung: Nucleolar protein 3 (NOL3 Produkte)

Synonyme: ARC antikoerper, FCM antikoerper, MYP antikoerper, NOP antikoerper, NOP30 antikoerper, B430311C09Rik antikoerper, MYC antikoerper, Nop30 antikoerper, Arc antikoerper, nucleolar protein 3 antikoerper, nucleolar protein 3 (apoptosis repressor with CARD domain) antikoerper, NOL3 antikoerper, Nol3 antikoerper

Hintergrund:

Synonyms: Apoptosis repressor with CARD, ARC, Muscle enriched cytoplasmic protein, MYC, Myp, NOP, Nop30, Nucleolar protein 3 apoptosis repressor with CARD domain, Nucleolar protein 3, Nucleolar protein of 30 kDa, NOL3_MOUSE .

Background: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD)bcontaining molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf 1, caspase 9 and caspase 2. Apoptosis repressor with CARD is a CARD domain containing protein that interacts with caspase 2 and 8 to inhibit enzymatic activity of caspase 8. Apoptosis repressor with CARD suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR 1, and DR3. The mRNA of Apoptosis repressor with CARD is primarily expressed in skeletal muscle and cardiac tissue. The nuclear isoform (1/Nop30) may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis.

Gen-ID: 8996