LGMN Antikörper (AA 201-300) (Alexa Fluor 350)
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- Target Alle LGMN Antikörper anzeigen
- LGMN (Legumain (LGMN))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LGMN Antikörper ist konjugiert mit Alexa Fluor 350
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Legumain
- Isotyp
- IgG
- Top Product
- Discover our top product LGMN Primärantikörper
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- Applikationshinweise
- FCM 1:20-100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LGMN (Legumain (LGMN))
- Andere Bezeichnung
- Legumain (LGMN Produkte)
- Synonyme
- AEP antikoerper, LGMN1 antikoerper, PRSC1 antikoerper, AI746452 antikoerper, AU022324 antikoerper, Prsc1 antikoerper, MGC64351 antikoerper, cb173 antikoerper, cb460 antikoerper, sb:cb173 antikoerper, zgc:76953 antikoerper, wu:fa98g05 antikoerper, wu:fj92g08 antikoerper, lgmn antikoerper, MGC88980 antikoerper, DELTA VACUOLAR PROCESSING ENZYME antikoerper, DELTAVPE antikoerper, delta vacuolar processing enzyme antikoerper, legumain antikoerper, legumain L homeolog antikoerper, delta vacuolar processing enzyme antikoerper, Legumain antikoerper, LGMN antikoerper, Lgmn antikoerper, lgmn.L antikoerper, lgmn antikoerper, DELTA-VPE antikoerper, MBOO_RS07785 antikoerper, Odosp_3582 antikoerper, LOC569153 antikoerper
- Hintergrund
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Synonyms: AEP, LGMN1, PRSC1, Legumain, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN
Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
- Gen-ID
- 5641
- UniProt
- Q99538
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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