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Integrin Alpha2b Antikörper (AA 351-450) (Alexa Fluor 555)

CD41 Reaktivität: Human, Ratte FACS, WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN902867
  • Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen
    Integrin Alpha2b (CD41)
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 114
    • 34
    • 20
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 76
    • 40
    • 25
    Kaninchen
    Klonalität
    • 97
    • 38
    • 1
    Polyklonal
    Konjugat
    • 56
    • 16
    • 12
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin Alpha2b Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 99
    • 44
    • 27
    • 26
    • 21
    • 19
    • 12
    • 12
    • 11
    • 10
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse,Cow,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
    Isotyp
    IgG
    Top Product
    Discover our top product CD41 Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Integrin Alpha2b (CD41)
    Andere Bezeichnung
    Integrin alpha 2b/CD41 (CD41 Produkte)
    Synonyme
    AI172977 antikoerper, CD41 antikoerper, CD41B antikoerper, GpIIb antikoerper, alphaIIb antikoerper, BDPLT16 antikoerper, BDPLT2 antikoerper, GP2B antikoerper, GPIIb antikoerper, GT antikoerper, GTA antikoerper, HPA3 antikoerper, integrin alpha 2b antikoerper, integrin subunit alpha 2b antikoerper, Itga2b antikoerper, ITGA2B antikoerper
    Hintergrund

    Synonyms: CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b

    Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

    Gen-ID
    16399
    UniProt
    Q9QUM0
    Pathways
    Integrin Complex
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