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Integrin Alpha2b Antikörper (FITC)

Name: Integrin Alpha2b Antikörper (FITC)
Brand: antibodies-online
SKU: ABIN94108
Price: 384.05 EUR
Availability: InStock

CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC antibody (20 μL reagent / 100 μL of peripheral whole blood).

FACS

Surface staining of human platelets with anti-human CD41 (MEM-06) PE.

FACS

Separation of human CD41 positive thrombocytes (red-filled) from CD41 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) FITC antibody (20 μL reagent / 100 μL of peripheral whole blood).

FACS

3 Abbildungen

Produktnummer ABIN94108

Datenblatt (PDF)

Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen

Integrin Alpha2b (CD41)
Reaktivität
122

34

21

5

5

4

3

2

2

2

1

1

1

1

1
Human
Wirt
83

41

25
Maus
Passende Sekundärantikörper
Klonalität
104

39

1
Monoklonal
Konjugat
58

16

13

12

6

4

4

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Integrin Alpha2b Antikörper ist konjugiert mit FITC
Applikation
105

46

33

28

20

19

13

13

11

10

8

5

3

3

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen

Leukocytes of patient suffering from LGL-type leukaemia.

Klon

MEM-06

Isotyp

IgG1

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Applikationshinweise

Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Kommentare

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Rekonstitution

No reconstitution is necessary.

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.
Avoid prolonged exposure to light.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target

Integrin Alpha2b (CD41)

Andere Bezeichnung

CD41 (CD41 Produkte)

Synonyme

AI172977 antikoerper, CD41 antikoerper, CD41B antikoerper, GpIIb antikoerper, alphaIIb antikoerper, BDPLT16 antikoerper, BDPLT2 antikoerper, GP2B antikoerper, GPIIb antikoerper, GT antikoerper, GTA antikoerper, HPA3 antikoerper, integrin alpha 2b antikoerper, integrin subunit alpha 2b antikoerper, Itga2b antikoerper, ITGA2B antikoerper

Hintergrund

Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA

Gen-ID

3674

UniProt

P08514

Pathways

Integrin Complex