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Integrin Alpha2b Antikörper

CD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated
Produktnummer ABIN94112
  • Target Alle Integrin Alpha2b (CD41) Antikörper anzeigen
    Integrin Alpha2b (CD41)
    Reaktivität
    • 124
    • 34
    • 21
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 83
    • 43
    • 25
    Maus
    Klonalität
    • 105
    • 40
    • 1
    Monoklonal
    Konjugat
    • 59
    • 17
    • 13
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin Alpha2b Antikörper ist unkonjugiert
    Applikation
    • 105
    • 48
    • 32
    • 28
    • 21
    • 19
    • 13
    • 13
    • 11
    • 10
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    The antibody HIP2 reacts with an extracellular epitope on beta (b) subunit of CD41 glycoprotein (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
    Kreuzreaktivität (Details)
    Human, Non-Human Primates
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Klon
    HIP2
    Isotyp
    IgG3
    Top Product
    Discover our top product CD41 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Wu: "[Production and application of anti-human platelet GP IIb/IIIa monoclonal antibodies]." in: Zhonghua yi xue za zhi, Vol. 69, Issue 8, pp. 427-30, 30, (1990) (PubMed).

  • Target
    Integrin Alpha2b (CD41)
    Andere Bezeichnung
    CD41b (CD41 Produkte)
    Synonyme
    AI172977 antikoerper, CD41 antikoerper, CD41B antikoerper, GpIIb antikoerper, alphaIIb antikoerper, BDPLT16 antikoerper, BDPLT2 antikoerper, GP2B antikoerper, GPIIb antikoerper, GT antikoerper, GTA antikoerper, HPA3 antikoerper, integrin alpha 2b antikoerper, integrin subunit alpha 2b antikoerper, Itga2b antikoerper, ITGA2B antikoerper
    Hintergrund
    Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,GT, GTA, GP2B, HPA3, GPIIb
    Gen-ID
    3674
    UniProt
    P08514
    Pathways
    Integrin Complex
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