FANCD2 Antikörper (AA 101-200) (Alexa Fluor 488)

Produktnummer ABIN896741

Produktdetails anti-FANCD2 Antikörper (Alexa Fluor 488)

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCD2 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FANCD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Andere Bezeichnung: FANCD2 (FANCD2 Produkte)

Synonyme: FANCD2 antikoerper, CG17269 antikoerper, CG31192 antikoerper, CG31194 antikoerper, Dmel\\CG17269 antikoerper, dmFANCD2 antikoerper, xfancd2 antikoerper, FA-D2 antikoerper, FA4 antikoerper, FACD antikoerper, FAD antikoerper, FAD2 antikoerper, FANCD antikoerper, 2410150O07Rik antikoerper, AU015151 antikoerper, BB137857 antikoerper, Fanconi anemia complementation group D2 antikoerper, CG17269 gene product from transcript CG17269-RA antikoerper, Fanconi anemia group D2 protein antikoerper, Fanconi anemia, complementation group D2 antikoerper, Fanconi anemia complementation group D2 L homeolog antikoerper, FANCD2 antikoerper, Fancd2 antikoerper, LOC100455970 antikoerper, fancd2 antikoerper, fancd2.L antikoerper

Hintergrund:

Synonyms: FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

Background: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

Gen-ID: 2177

Pathways: DNA Reparatur