FANCD2 Antikörper (N-Term)

Produktnummer ABIN540721

Produktdetails anti-FANCD2 Antikörper

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Verwendungszweck: Rabbit polyclonal antibody raised against partial recombinant FANCD2.

Spezifität: This antibody is specific to FANCD2.

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to N-terminus of human FANCD2.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence (1:200-1:500)
Western Blot (1:10000-1:20000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-5 μg/mL)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-FANCD2 Antikörper (ABIN540721)

Bekker-Jensen, Lukas, Kitagawa, Melander, Kastan, Bartek, Lukas: "Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks." in: The Journal of cell biology, Vol. 173, Issue 2, pp. 195-206, (2006) (PubMed).

Tremblay, Pintor Dos Reis, Bradley, Galloni, Perez-Ordonez, Freeman, Brown, Gilbert, Gullane, Irish, Kamel-Reid: "Young patients with oral squamous cell carcinoma: study of the involvement of GSTP1 and deregulation of the Fanconi anemia genes." in: Archives of otolaryngology--head & neck surgery, Vol. 132, Issue 9, pp. 958-66, (2006) (PubMed).

Mukhopadhyay, Leung, Hicks, Hastings, Youssoufian, Plon: "Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia." in: The Journal of cell biology, Vol. 175, Issue 2, pp. 225-35, (2006) (PubMed).

Stiff, Reis, Alderton, Woodbine, ODriscoll, Jeggo: "Nbs1 is required for ATR-dependent phosphorylation events." in: The EMBO journal, Vol. 24, Issue 1, pp. 199-208, (2005) (PubMed).

Rothfuss, Grompe: "Repair kinetics of genomic interstrand DNA cross-links: evidence for DNA double-strand break-dependent activation of the Fanconi anemia/BRCA pathway." in: Molecular and cellular biology, Vol. 24, Issue 1, pp. 123-34, (2003) (PubMed).

Details zu FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Andere Bezeichnung: FANCD2 (FANCD2 Produkte)

Synonyme: FANCD2 antikoerper, CG17269 antikoerper, CG31192 antikoerper, CG31194 antikoerper, Dmel\\CG17269 antikoerper, dmFANCD2 antikoerper, xfancd2 antikoerper, FA-D2 antikoerper, FA4 antikoerper, FACD antikoerper, FAD antikoerper, FAD2 antikoerper, FANCD antikoerper, 2410150O07Rik antikoerper, AU015151 antikoerper, BB137857 antikoerper, Fanconi anemia complementation group D2 antikoerper, CG17269 gene product from transcript CG17269-RA antikoerper, Fanconi anemia group D2 protein antikoerper, Fanconi anemia, complementation group D2 antikoerper, Fanconi anemia complementation group D2 L homeolog antikoerper, FANCD2 antikoerper, Fancd2 antikoerper, LOC100455970 antikoerper, fancd2 antikoerper, fancd2.L antikoerper

Gen-ID: 2177

Pathways: DNA Reparatur