BRIP1 Antikörper (Alexa Fluor 647)

Produktnummer ABIN884389

Produktdetails anti-BRIP1 Antikörper (Alexa Fluor 647)

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Huhn, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRIP1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: Excitation / Emission Wavelengths: 652nm/668nm

Kreuzreaktivität: Maus, Ratte (Rattus), Kaninchen, Rind (Kuh), Schwein, Pferd, Hund, Huhn

Aufreinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BACH1
Please inquire for sequence information.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu BRIP1

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Andere Bezeichnung: BACH1/BRIP1 (BRIP1 Produkte)

Synonyme: MGC68622 antikoerper, BRIP1 antikoerper, fancj antikoerper, si:ch211-158l18.1 antikoerper, BACH1 antikoerper, FANCJ antikoerper, OF antikoerper, 3110009N10Rik antikoerper, 8030460J03Rik antikoerper, Bach1 antikoerper, FACJ antikoerper, Fancj antikoerper, BRCA1 interacting protein C-terminal helicase 1 antikoerper, BRCA1 interacting protein C-terminal helicase 1 L homeolog antikoerper, Brip1 antikoerper, brip1.L antikoerper, BRIP1 antikoerper, brip1 antikoerper

Hintergrund: BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination, and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
Synonym: BACH 1, BRIP1, BACH-1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, BRIP-1, FANCJ, ATP dependent RNA helicase BRIP1, Fanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF antibody Protein FACJ.

Molekulargewicht: 130kDa

Gen-ID: 571

Pathways: DNA Reparatur