MNAT1 Antikörper (AA 51-150)

Produktnummer ABIN872731

Produktdetails anti-MNAT1 Antikörper

Target: MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

Bindungsspezifität: AA 51-150

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MNAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MNAT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MNAT1

Target: MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))

Andere Bezeichnung: MNAT1 (MNAT1 Produkte)

Synonyme: F6I18.270 antikoerper, F6I18_270 antikoerper, Afu4g08900 antikoerper, E130115E11Rik antikoerper, MAT1 antikoerper, P36 antikoerper, zgc:101599 antikoerper, CAP35 antikoerper, RNF66 antikoerper, TFB3 antikoerper, cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein antikoerper, CDK-activating kinase assembly factor MAT1 antikoerper, MNAT1, CDK activating kinase assembly factor antikoerper, menage a trois 1 antikoerper, MNAT CDK-activating kinase assembly factor 1 antikoerper, MNAT1, CDK activating kinase assembly factor L homeolog antikoerper, AT4G30820 antikoerper, AFUA_4G08900 antikoerper, NFIA_107260 antikoerper, CpipJ_CPIJ001565 antikoerper, AFLA_110530 antikoerper, BDBG_00548 antikoerper, TERG_06789 antikoerper, Tsp_08309 antikoerper, mnat1 antikoerper, Mnat1 antikoerper, MNAT1 antikoerper, mnat1.L antikoerper

Hintergrund:

Synonyms: MAT1, TFB3, CAP35, RNF66, CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, Menage a trois, RING finger protein 66, RING finger protein MAT1, p35, p36, MNAT1

Background: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.

Gen-ID: 4331

UniProt: P51948

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase