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CD22 Antikörper (AA 839-843)

CD22 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN871517
  • Target Alle CD22 Antikörper anzeigen
    CD22 (CD22 Molecule (CD22))
    Bindungsspezifität
    • 16
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 839-843
    Reaktivität
    • 154
    • 50
    • 24
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 101
    • 62
    • 14
    Kaninchen
    Klonalität
    • 125
    • 54
    Polyklonal
    Konjugat
    • 82
    • 15
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD22 Antikörper ist unkonjugiert
    Applikation
    • 112
    • 71
    • 46
    • 39
    • 38
    • 19
    • 13
    • 11
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects endogenous level of total CD22 protein.
    Aufreinigung
    Affinity purified
    Immunogen
    Peptide sequence around AA 839-843 (N-V-D-Y-V) derived from Human CD22. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product CD22 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    CD22 (CD22 Molecule (CD22))
    Andere Bezeichnung
    CD22 (CD22 Produkte)
    Synonyme
    A530093D23 antikoerper, Lyb-8 antikoerper, Lyb8 antikoerper, SIGLEC-2 antikoerper, SIGLEC2 antikoerper, siglec-2 antikoerper, CD22 antigen antikoerper, CD22 molecule antikoerper, Cd22 antikoerper, CD22 antikoerper
    Hintergrund
    Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to a-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
    Molekulargewicht
    140 kDa
    Gen-ID
    933
    NCBI Accession
    NP_001762
    UniProt
    P20273
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