ADAMTS13 Antikörper (AA 401-500)

Produktnummer ABIN758891

Produktdetails anti-ADAMTS13 Antikörper

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Bindungsspezifität: AA 401-500

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADAMTS13

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ADAMTS13

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Andere Bezeichnung: ADAMTS13 (ADAMTS13 Produkte)

Synonyme: ADAMTS13 antikoerper, ADAM-TS13 antikoerper, ADAMTS-13 antikoerper, C9orf8 antikoerper, VWFCP antikoerper, vWF-CP antikoerper, Gm710 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 13 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 13 antikoerper, ADAMTS13 antikoerper, Adamts13 antikoerper, adamts13 antikoerper

Hintergrund:

Synonyms: Cleaves the vWF multimers in plasma into smaller forms. Von Willebrand factor cleaving protease, A disintegrin and metalloproteinase with thrombospondin mots 13, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 13, A disintegrin like and metalloprotease with thrombospondin type 1 mot 13, ADAM metallopeptidase with thrombospondin type 1 mot 13, ADAM TS 13, ADAM TS13, ADAM-TS 13, ADAM-TS13, ADAMTS 13, ADAMTS-13, ADAMTS13, ADAMTS13 protein, ATS13_HUMAN, C9orf8, TTP, von Willebrand factor-cleaving protease, vWF cleaving protease, vWF CP, vWF-cleaving protease, vWF-CP, vWFCP.

Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].

Gen-ID: 11093

UniProt: Q76LX8