ADAMTS13 Produkte
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
Kategorien
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].
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Ausgewählte ADAMTS13 Kategorien
ADAMTS13 Antikörper
High quality antibodies with extensive validation data.
ADAMTS13 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAMTS13 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ADAMTS13 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7432937
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN564816
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN6259782
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ADAMTS13 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953460
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964600
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964599
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ADAMTS13 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305888
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3135899
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505139
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ADAMTS13 Produkten
: "Neutrophil Protease Cleavage of Von Willebrand Factor in Glomeruli - An Anti-thrombotic Mechanism in the Kidney." in: EBioMedicine, Vol. 16, pp. 302-311, (2017) (PubMed).: "The Expression of Tristetraprolin and Its Relationship with Urinary Proteins in Patients with Diabetic Nephropathy." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141471, (2016) (PubMed).
: "Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome." in: Blood, Vol. 122, Issue 8, pp. 1487-93, (2013) (PubMed).
: "The interaction between factor H and Von Willebrand factor." in: PLoS ONE, Vol. 8, Issue 8, pp. e73715, (2013) (PubMed).
: "Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat)." in: The Journal of biological chemistry, Vol. 287, Issue 53, pp. 44361-71, (2012) (PubMed).
: "Detection of a secreted metalloprotease within the nuclei of liver cells." in: Molecular bioSystems, Vol. 7, Issue 6, pp. 2012-8, (2011) (PubMed).
: "Dilated capillaries, disorganized collagen fibers and differential gene expression in periodontal ligaments of hypomorphic fibrillin-1 mice." in: Cell and tissue research, Vol. 341, Issue 3, pp. 381-95, (2010) (PubMed).
: "Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage." in: Blood, Vol. 114, Issue 24, pp. 5102-11, (2009) (PubMed).
: "Fibrinogen-induced endothelin-1 production from endothelial cells." in: American journal of physiology. Cell physiology, Vol. 296, Issue 4, pp. C840-7, (2009) (PubMed).
: "Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy." in: The Journal of biological chemistry, Vol. 283, Issue 15, pp. 9531-42, (2008) (PubMed).
Synonyme und alternative Namen zu ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13 (ADAMTS13), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13), ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13), ADAM metallopeptidase with thrombospondin type 1 motif 13 (Adamts13), ADAM-TS13, ADAMTS-13, ADAMTS13, C9orf8, Gm710, vWF-CP, VWFCPBezeichner auf Proteinebene für ADAMTS13
- ADAM metallopeptidase with thrombospondin type 1 motif, 13
- A disintegrin and metalloproteinase with thrombospondin motifs 13
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
- vWF-cleaving protease
- von Willebrand factor-cleaving protease
- ADAM-TS 13
- ADAM-TS13
- ADAMTS-13
- ADAMTS13 isoform IAP-b
- vWF-CP mRNA for von Willebrand factor-cleaving
- ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like
- A disintegrin and metalloproteinase with thrombospondin motifs 13-like
- a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
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