ADAMTS4 Produkte
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
Kategorien
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008].
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Ausgewählte ADAMTS4 Kategorien
ADAMTS4 Antikörper
High quality antibodies with extensive validation data.
ADAMTS4 ELISA Kits
Reliable ELISA kits for a wide range of species.
ADAMTS4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ADAMTS4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7072947
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7142886
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN391642
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ADAMTS4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6974698
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (8)
- (1)
Kat. Nr.
ABIN6953462
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rabbit
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953464
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ADAMTS4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305901
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305903
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3089861
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ADAMTS4 Produkten
: "MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 44, Issue 1, pp. 38-52, (2018) (PubMed).: "AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice." in: Scientific reports, Vol. 7, pp. 43245, (2017) (PubMed).
: "VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts." in: Journal of cellular and molecular medicine, Vol. 20, Issue 4, pp. 678-87, (2016) (PubMed).
: "From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases." in: International wound journal, (2016) (PubMed).
: "Parathyroid hormone(1-34) exhibits more comprehensive effects than celecoxib in cartilage metabolism and maintaining subchondral bone micro-architecture in meniscectomized guinea pigs." in: Osteoarthritis and cartilage, Vol. 24, Issue 6, pp. 1103-12, (2016) (PubMed).
: "Healthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12: Induction by IL-1β and Fibronectin and Contribution to ..." in: The American journal of pathology, Vol. 186, Issue 9, pp. 2449-61, (2016) (PubMed).
: "Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat." in: BMC musculoskeletal disorders, Vol. 16, pp. 342, (2016) (PubMed).
: "A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes." in: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, (2015) (PubMed).
: "Lack of anti-inflammatory and anti-catabolic effects on basal inflamed osteoarthritic chondrocytes or synoviocytes by adipose stem cell-conditioned medium." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 23, Issue 11, pp. 2045-57, (2015) (PubMed).
: "Differential expression patterns of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) -1, -4, -5, and -14 in human placenta and gestational trophoblastic diseases." in: Archives of pathology & laboratory medicine, Vol. 138, Issue 5, pp. 643-50, (2014) (PubMed).
Synonyme und alternative Namen zu ADAMTS4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4), ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4), ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4), ADAM metallopeptidase with thrombospondin type 1 motif 4 (Adamts4), 3830423K05, ADAM-TS4, ADAMTS-2, ADAMTS-4, ADAMTS4, ADMP-1, mKIAA0688Bezeichner auf Proteinebene für ADAMTS4
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- ADAM-TS 4
- ADAMTS-4
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4
- aggrecanase-1
- ADAM-TS4
- Aggrecanase
- a disintegrin and metallopeptidase with thrombospondin motifs 4
- a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
- ADMP-1
- ADAM metallopeptidase with thrombospondin type 1 motif, 4
- A disintegrin and metalloproteinase with thrombospondin motifs 4-like
- disintegrin and metalloproteinase with thrombospondin motifs 2
- a disintegrin and metalloproteinase with thrombospondin motifs 4
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