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ADAM8 Produkte

(ADAM Metallopeptidase Domain 8 (ADAM8))
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009].

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Ausgewählte ADAM8 Kategorien

ADAM8 Antikörper

High quality antibodies with extensive validation data.

ADAM8 ELISA Kits

Reliable ELISA kits for a wide range of species.

ADAM8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ADAM8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
  • (6)
Kat. Nr. ABIN7193315
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN1866534
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7150062
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ADAM8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
  • (1)
Kat. Nr. ABIN415444
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6961974
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953454
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ADAM8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7273801
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7273803
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121692
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ADAM8 Produkten

Schick, Babendreyer, Wozniak, Awan, Noels, Liehn, Bartsch, Vlacil, Grote, Zayat, Goetzenich, Ludwig, Dreymueller: "Elevated expression of the metalloproteinase ADAM8 associates with vascular diseases in mice and humans." in: Atherosclerosis, Vol. 286, pp. 163-171, (2019) (PubMed).

Chung, Kim, Choi, Lee, Lim: "A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer." in: Yonsei medical journal, Vol. 60, Issue 8, pp. 713-719, (2019) (PubMed).

Das, Romagnoli, Mineva, Barillé-Nion, Jézéquel, Campone, Sonenshein: "miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells." in: Breast cancer research : BCR, Vol. 18, Issue 1, pp. 40, (2016) (PubMed).

Schlomann, Koller, Conrad, Ferdous, Golfi, Garcia, Höfling, Parsons, Costa, Soper, Bossard, Hagemann, Roshani, Sewald, Ketchem, Moss, Rasmussen, Miller, Lauffenburger, Tuveson, Nimsky, Bartsch: "ADAM8 as a drug target in pancreatic cancer." in: Nature communications, Vol. 6, pp. 6175, (2015) (PubMed).

Gómez-Gaviro, Domínguez-Luis, Canchado, Calafat, Janssen, Lara-Pezzi, Fourie, Tugores, Valenzuela-Fernández, Mollinedo, Sánchez-Madrid, Díaz-González: "Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 12, pp. 8053-63, (2007) (PubMed).

Johansson, Lye, Barthel, Duffy, Annis, Mosher: "Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 4, pp. 413-22, (2004) (PubMed).

Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).

Li, Sorensen, Brooke, Urness, Davis, Taylor, Boak, Wendel: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).

Yoshiyama, Higuchi, Kataoka, Matsuura, Yamamoto: "CD156 (human ADAM8): expression, primary amino acid sequence, and gene location." in: Genomics, Vol. 41, Issue 1, pp. 56-62, (1997) (PubMed).

Bellón, Corbí, Lastres, Calés, Cebrián, Vera, Cheifetz, Massague, Letarte, Bernabéu: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).

Synonyme und alternative Namen zu ADAM8

ADAM metallopeptidase domain 8 (ADAM8), a disintegrin and metalloproteinase domain 8 (LOC100304737), a disintegrin and metallopeptidase domain 8 (Adam8), ADAM metallopeptidase domain 8a (adam8a), ADAM metallopeptidase domain 8 (Adam8), a disintegrin and metalloproteinase domain 8 (adam8), adam8, ADAM8, CD156, CD156a, E430039A18Rik, MS2, reprolysin, RGD1566394, si:zc217g15.7, zgc:64059

Bezeichner auf Proteinebene für ADAM8

  • a disintegrin and metalloproteinase domain 8
  • cell surface antigen MS2
  • disintegrin and metalloproteinase domain-containing protein 8
  • human leukocyte differentiation antigen
  • ADAM 8
  • a disintegrin and metalloprotease domain (ADAM) 8
  • a disintegrin and metalloprotease domain 8
  • macrophage cysteine-rich glycoprotein
  • CD156a
  • metalloprotease
  • ADAM metallopeptidase domain 8
  • a disintegrin and metallopeptidase domain 8
  • disintegrin and metalloproteinase domain-containing protein 8-like
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