ADAMTS13 Antikörper (AA 829-858)

Produktnummer ABIN391641

Produktdetails anti-ADAMTS13 Antikörper

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Bindungsspezifität: AA 829-858

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAMTS13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ADAMTS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 829-858 amino acids from the Central region of human ADAMTS13.

Klon: RB18029

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ADAMTS13

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Andere Bezeichnung: ADAMTS13 (ADAMTS13 Produkte)

Synonyme: ADAMTS13 antikoerper, ADAM-TS13 antikoerper, ADAMTS-13 antikoerper, C9orf8 antikoerper, VWFCP antikoerper, vWF-CP antikoerper, Gm710 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 13 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 13 antikoerper, ADAMTS13 antikoerper, Adamts13 antikoerper, adamts13 antikoerper

Hintergrund: ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.

Molekulargewicht: 153604

Gen-ID: 11093

NCBI Accession: NP_620594, NP_620595, NP_620596

UniProt: Q76LX8