FE65 Antikörper (pSer175)
-
- Target Alle FE65 (APBB1) Antikörper anzeigen
- FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
-
Bindungsspezifität
- pSer175
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FE65 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human APBB1 around the phosphorylation site of Ser175 [LS(p-S)PP]
- Isotyp
- IgG
- Top Product
- Discover our top product APBB1 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
- Andere Bezeichnung
- APBB1 (APBB1 Produkte)
- Synonyme
- FE65 antikoerper, MGC:9072 antikoerper, RIR antikoerper, apbb1 antikoerper, MGC80654 antikoerper, Fe65 antikoerper, Rir antikoerper, amyloid beta precursor protein binding family B member 1 antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 1 antikoerper, APBB1 antikoerper, apbb1.L antikoerper, Apbb1 antikoerper
- Hintergrund
-
Synonyms: Adaptor protein FE65a2, Amyloid beta A4 precursor protein binding family B member 1, Amyloid beta A4 precursor protein binding family B, Amyloid beta A4 precursor protein binding family B member 1, Amyloid beta precursor protein binding family B member 1, APBB 1, APBB1, FE 65, Fe65 protein, MGC 9072, MGC9072, Protein Fe65, RIR, Stat like protein, Fe-65 Protein, APBB1_HUMAN.
Background: The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Gen-ID
- 322
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
-