POLR2C Antikörper (AA 225-275)

Produktnummer ABIN7454959

Produktdetails anti-POLR2C Antikörper

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Bindungsspezifität: AA 225-275

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-RPB3 Antibody, Affinity Purified

Homologie: Bovine

Aufreinigung: Affinity Purified

Immunogen: Between AA 225 and 275

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Andere Bezeichnung: RPB3 (POLR2C Produkte)

Synonyme: RPB3 antikoerper, RPB31 antikoerper, hRPB33 antikoerper, hsRPB3 antikoerper, 33kDa antikoerper, Rpo2-3 antikoerper, mRBP31 antikoerper, zgc:56285 antikoerper, wu:fk48d01 antikoerper, MGC76329 antikoerper, MGC81245 antikoerper, POLR2C antikoerper, polr2c antikoerper, rpb3 antikoerper, RNA polymerase II subunit C antikoerper, polymerase (RNA) II (DNA directed) polypeptide C antikoerper, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa S homeolog antikoerper, POLR2C antikoerper, Polr2c antikoerper, polr2c antikoerper, polr2c.S antikoerper

Hintergrund: Background: RPB3 (RNA polymerase II subunit 3) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft [taken from the Universal Protein Resource (UniProt) P19387].

Gen-ID: 5432

NCBI Accession: NP_116558

UniProt: P19387

Pathways: Regulatorische RNA Pathways