POLR2C Antikörper (C-Term)

Produktnummer ABIN1881670

Produktdetails anti-POLR2C Antikörper

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Bindungsspezifität: AA 200-228, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This POLR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the C-terminal region of human POLR2C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000. IHC-P: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-POLR2C Antikörper (ABIN1881670)

Dammann, Pfeifer: "Cloning and characterization of the human RNA polymerase I subunit hRPA40." in: Biochimica et biophysica acta, Vol. 1396, Issue 2, pp. 153-7, (1998) (PubMed).

Pati, Weissman: "The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8400-3, (1990) (PubMed).

Details zu POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Andere Bezeichnung: POLR2C (POLR2C Produkte)

Synonyme: RPB3 antikoerper, RPB31 antikoerper, hRPB33 antikoerper, hsRPB3 antikoerper, 33kDa antikoerper, Rpo2-3 antikoerper, mRBP31 antikoerper, zgc:56285 antikoerper, wu:fk48d01 antikoerper, MGC76329 antikoerper, MGC81245 antikoerper, POLR2C antikoerper, polr2c antikoerper, rpb3 antikoerper, RNA polymerase II subunit C antikoerper, polymerase (RNA) II (DNA directed) polypeptide C antikoerper, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa antikoerper, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa S homeolog antikoerper, POLR2C antikoerper, Polr2c antikoerper, polr2c antikoerper, polr2c.S antikoerper

Hintergrund: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).

Molekulargewicht: 31441

NCBI Accession: NP_116558

UniProt: P19387

Pathways: Regulatorische RNA Pathways