PSMD12 Antikörper (AA 1-50)

Produktnummer ABIN7452964

Produktdetails anti-PSMD12 Antikörper

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Bindungsspezifität: AA 1-50

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit anti-PSMD12 Antibody, Affinity Purified

Homologie: Mouse,Bovine,Orangutan

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: Not recommended

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PSMD12

Target: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Andere Bezeichnung: PSMD12 (PSMD12 Produkte)

Synonyme: wu:fb38a06 antikoerper, wu:fc34f08 antikoerper, wu:fc49f02 antikoerper, PSMD12 antikoerper, rpn5 antikoerper, Rpn5 antikoerper, p55 antikoerper, 1500002F15Rik antikoerper, AI480719 antikoerper, P55 antikoerper, proteasome 26S subunit, non-ATPase 12 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antikoerper, psmd12 antikoerper, PSMD12 antikoerper, Psmd12 antikoerper

Hintergrund: Background: Proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 is a non-ATPase subunit of the 19S regulator. [taken from NCBI Entrez Gene (Gene ID: 5718)].

Gen-ID: 5718

NCBI Accession: NP_002807

UniProt: O00232

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway