PSMD12 Antikörper (N-Term)
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- Target Alle PSMD12 Antikörper anzeigen
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PSMD12 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MADGGSERAD GRIVKMEVDY SATVDQRLPE CAKLAKEGRL QEVIETLLSL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PSMD12. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PSMD12
- Top Product
- Discover our top product PSMD12 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 456 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
- Andere Bezeichnung
- PSMD12 (PSMD12 Produkte)
- Synonyme
- wu:fb38a06 antikoerper, wu:fc34f08 antikoerper, wu:fc49f02 antikoerper, PSMD12 antikoerper, rpn5 antikoerper, Rpn5 antikoerper, p55 antikoerper, 1500002F15Rik antikoerper, AI480719 antikoerper, P55 antikoerper, proteasome 26S subunit, non-ATPase 12 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antikoerper, psmd12 antikoerper, PSMD12 antikoerper, Psmd12 antikoerper
- Hintergrund
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.
Alias Symbols: MGC75406, p55, Rpn5
Protein Interaction Partner: FUS, HUWE1, SUMO2, UBC, PSMD14, RNF2, KIAA0368, HNRNPA0, TXNL1, SQSTM1, PSMD11, PSMD3, PSMD1, PSMC6, PSMC5, PSMC4, PSMC2, PSMC1, FLNC, FLNB, KCMF1, PARK2, BAG3, RNF11, NPM1, NOS2, PSMD6, PSMD13, PSMD7, UGGT1, PSME3, USP14, PSME1, PSMD10, PSMD8, PSMD4, PSM
Protein Size: 456 - Molekulargewicht
- 50 kDa
- Gen-ID
- 5718
- NCBI Accession
- NM_002816, NP_002807
- UniProt
- O00232
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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