PPARGC1B Antikörper (AA 850-950)

Produktnummer ABIN7269253

Produktdetails anti-PPARGC1B Antikörper

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Bindungsspezifität: AA 850-950

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARGC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PGC1 beta Rabbit pAb

Sequenz: SSRELKRRFE VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA LRKRNEPSFQ LSYGGLRHFC WPRYTDYDSN SEEALPASGK SKYEAMDFDS L

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 850-950 of human PGC1 beta (NP_001166170.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Andere Bezeichnung: PPARGC1B (PPARGC1B Produkte)

Synonyme: PPARGC1B antikoerper, 4631412G21Rik antikoerper, Perc antikoerper, PGC1beta antikoerper, ERRL1 antikoerper, PERC antikoerper, PGC-1(beta) antikoerper, PGC1B antikoerper, PPARG coactivator 1 beta antikoerper, peroxisome proliferative activated receptor, gamma, coactivator 1 beta antikoerper, PPARGC1B antikoerper, Ppargc1b antikoerper

Hintergrund: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.,PPARGC1B,ERRL1,PERC,PGC-1(beta),PGC1B,PPARGC1B,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Lipids,Fatty Acids,PPARGC1B

Molekulargewicht: 106kDa/108kDa/110kDa/112kDa/113kDa

Gen-ID: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha