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PPARGC1B Produkte

(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Kategorien

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

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Ausgewählte PPARGC1B Kategorien

PPARGC1B Antikörper

High quality antibodies with extensive validation data.

PPARGC1B ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene PPARGC1B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN872354
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (4)
Kat. Nr. ABIN2683008
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7243736
Menge 200 μL
Datenblatt Datenblatt

Empfohlene PPARGC1B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN4993641
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6220445
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PPARGC1B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3136747
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094725
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505260
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PPARGC1B Produkten

Chang, Lee, Lee, Park, Chung, Park: "Functional Characterization of Exonic Variants of the PPARGC1B Gene in Coregulation of Estrogen Receptor Alpha." in: DNA and cell biology, Vol. 35, Issue 7, pp. 314-21, (2016) (PubMed).

Stevens, Lee, Kang, Lee, Lee, Bower, Jiang, Kang, Andrabi, Dawson, Shin, Dawson: "Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 37, pp. 11696-701, (2015) (PubMed).

Zhou, Ma, Mo, Zheng, Chen, Wei, Dai et al.: "Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." in: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).

Lou, Zhang, Lucchinetti, Heck, Affolter, Gandhi, Kienesberger, Hersberger, Clanachan, Zaugg: "Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury." in: Cardiovascular research, Vol. 97, Issue 2, pp. 251-61, (2013) (PubMed).

Kemper, Zhao, Duckles, Krause: "Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 1, pp. 122-8, (2013) (PubMed).

Kammerer, Gutzwiller, Stauffer, Delhon, Seltenmeyer, Fournier: "Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform." in: Molecular and cellular endocrinology, Vol. 369, Issue 1-2, pp. 150-60, (2013) (PubMed).

Liu, Zhou, Zhang, Tu, Xia, Wang, Zhou, Zhang, Wu, Gao, He, Zhai: "Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis." in: Journal of lipid research, Vol. 53, Issue 3, pp. 358-67, (2012) (PubMed).

Liu, Hong, Wen, Han, Zuo, Liu, Cao: "Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance." in: American journal of physiology. Endocrinology and metabolism, Vol. 297, Issue 4, pp. E898-906, (2010) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).

Mathai, Bonen, Benton, Robinson, Graham: "Rapid exercise-induced changes in PGC-1alpha mRNA and protein in human skeletal muscle." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 105, Issue 4, pp. 1098-105, (2008) (PubMed).

Synonyme und alternative Namen zu PPARGC1B

PPARG coactivator 1 beta (PPARGC1B), peroxisome proliferative activated receptor, gamma, coactivator 1 beta (Ppargc1b), PPARG coactivator 1 beta (Ppargc1b), 4631412G21Rik, ERRL1, Perc, PERC, PGC-1(beta), PGC1B, PGC1beta, PPARGC1B

Bezeichner auf Proteinebene für PPARGC1B

  • peroxisome proliferator-activated receptor gamma, coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1-beta-like
  • ERR ligand 1
  • PGC-1-beta
  • PGC-1beta
  • PGC-1beta/ERRL1
  • PPAR gamma coactivator-1beta protein
  • PPAR-gamma coactivator 1-beta
  • PPARGC-1-beta
  • peroxisome proliferator-activated receptor gamma coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1-beta
  • peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1beta-2a
  • PGC-1-related estrogen receptor alpha coactivator
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