PPARGC1B Antikörper (AA 195-414)

Produktnummer ABIN2683008

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PPARGC1B in ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PPARGC1B Antikörper (AA 195-414) (ABIN2683008)

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPARGC1B Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: 6C3F6

Produktdetails anti-PPARGC1B Antikörper

Bindungsspezifität: AA 195-414

Verwendungszweck: PPARGC1B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Andere Bezeichnung: PPARGC1B

Hintergrund: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 113.2 kDa

Gen-ID: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha