PPARGC1B Antikörper (AA 195-414)

Produktnummer ABIN2683008

Produktdetails anti-PPARGC1B Antikörper

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Bindungsspezifität: AA 195-414

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPARGC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. coli.

Klon: 6C3F6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Andere Bezeichnung: PPARGC1B (PPARGC1B Produkte)

Synonyme: PPARGC1B antikoerper, 4631412G21Rik antikoerper, Perc antikoerper, PGC1beta antikoerper, ERRL1 antikoerper, PERC antikoerper, PGC-1(beta) antikoerper, PGC1B antikoerper, PPARG coactivator 1 beta antikoerper, peroxisome proliferative activated receptor, gamma, coactivator 1 beta antikoerper, PPARGC1B antikoerper, Ppargc1b antikoerper

Hintergrund:

Description: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Aliases: PERC, ERRL1, PGC1B, PGC-1(beta)

Molekulargewicht: 113.2 kDa

Gen-ID: 133522

HGNC: 133522

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha