PPARD Produkte
(Peroxisome Proliferator-Activated Receptor delta (PPARD))
Kategorien
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
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Ausgewählte PPARD Kategorien
PPARD Antikörper
High quality antibodies with extensive validation data.
PPARD ELISA Kits
Reliable ELISA kits for a wide range of species.
PPARD Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PPARD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, PLA
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN562332
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, ELISA
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN105799
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN519066
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PPARD ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969235
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958501
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958502
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PPARD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315833
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1315832
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3133837
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PPARD Produkten
: "Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181052, (2017) (PubMed).: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).
: "PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms." in: Journal of cellular biochemistry, Vol. 116, Issue 5, pp. 844-55, (2015) (PubMed).
: "Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation." in: The Journal of biological chemistry, Vol. 290, Issue 51, pp. 30306-20, (2015) (PubMed).
: "PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting." in: PLoS ONE, Vol. 8, Issue 3, pp. e59726, (2013) (PubMed).
: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).
: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).
: "Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 298, Issue 6, pp. E1140-9, (2010) (PubMed).
: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
Synonyme und alternative Namen zu PPARD
peroxisome proliferator activated receptor delta (PPARD), peroxisome proliferator activator receptor delta (Ppard), peroxisome proliferator activated receptor delta S homeolog (ppard.S), peroxisome proliferator activated receptor delta (ppard), peroxisome proliferator-activated receptor delta (Ppard), peroxisome proliferator activated receptor delta (Ppard), FAAR, NR1C2, Nr1c2, NUC-1, NUC1, NUCI, NUCII, PPAR-beta, PPAR-D/B, PPAR-delta, PPARB, Pparb, pparb, Pparb/d, PPARBETA, ppard, PPARD, PPARdelta, PPAR[b]Bezeichner auf Proteinebene für PPARD
- PPAR-beta
- PPAR-delta
- nuclear hormone receptor 1
- nuclear receptor subfamily 1 group C member 2
- peroxisome proliferator-activated nuclear receptor beta/delta variant 2
- peroxisome proliferator-activated receptor beta
- PPARdelta/beta
- Peroxisome proliferator-activated receptor beta
- peroxisome proliferator-activated receptor delta
- peroxisome proliferative activated receptor, delta
- peroxisome proliferator-activated receptor delta-like
- peroxisome proliferator activated receptor delta
- peroxisome proliferator activator receptor beta
- peroxisome proliferator activator receptor, delta
- peroxisome proliferator activator receptor delta
- peroxisome proliferator activated receptor delta/beta
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