NR2F6 Antikörper (AA 1-55)
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- Target Alle NR2F6 Antikörper anzeigen
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
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Bindungsspezifität
- AA 1-55
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR2F6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- NR2F6 Rabbit pAb
- Sequenz
- MAMVTGGWGG PGGDTNGVDK AGGYPRAAED DSASPPGAAS DAEPGDEERP GLQVD
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-55 of human NR2F6 (NP_005225.2).
- Isotyp
- IgG
- Top Product
- Discover our top product NR2F6 Primärantikörper
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- Applikationshinweise
- WB,1:200 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
- Andere Bezeichnung
- NR2F6 (NR2F6 Produkte)
- Synonyme
- EAR-2 antikoerper, EAR2 antikoerper, ERBAL2 antikoerper, AV090102 antikoerper, COUP-TF3 antikoerper, Erbal2 antikoerper, COUP(II) antikoerper, NR2F6 antikoerper, couptf2 antikoerper, fc94g11 antikoerper, wu:fc94g11 antikoerper, zgc:77259 antikoerper, ear-2 antikoerper, ear2 antikoerper, erbal2 antikoerper, nr2f6l antikoerper, wu:fc72d04 antikoerper, zgc:77260 antikoerper, nuclear receptor subfamily 2 group F member 6 antikoerper, nuclear receptor subfamily 2, group F, member 6 antikoerper, nuclear receptor subfamily 2, group F, member 6a antikoerper, nuclear receptor subfamily 2 group F member 6 L homeolog antikoerper, nuclear receptor subfamily 2, group F, member 6b antikoerper, NR2F6 antikoerper, Nr2f6 antikoerper, nr2f6a antikoerper, nr2f6.L antikoerper, nr2f6 antikoerper, nr2f6b antikoerper
- Hintergrund
- Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC.,NR2F6,EAR-2,EAR2,ERBAL2,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,NR2F6
- Molekulargewicht
- 42kDa
- Gen-ID
- 2063
- UniProt
- P10588
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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