NR2F6 Antikörper

Produktnummer ABIN2749193

Produktdetails anti-NR2F6 Antikörper

Target: NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NR2F6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody EM-51 recognizes NR2F6, a transcriptional repressor (intracellular antigen) expressed mainly in the heart, placenta, liver, skeletal muscle, kidney and pancreas, but also e.g. in T cell subpopulations.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Recombinant human NR2F6 protein expressed in E. coli

Klon: EM-51

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Western blotting: Positive control: HEK293T/17/NR2F6/Ha-tag transfectants, negative control: HEK293T/17 cells.
Flow cytometry: Recommended dilution: 3-9 μg/mL. Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu NR2F6

Target: NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))

Andere Bezeichnung: NR2F6 (NR2F6 Produkte)

Synonyme: EAR-2 antikoerper, EAR2 antikoerper, ERBAL2 antikoerper, AV090102 antikoerper, COUP-TF3 antikoerper, Erbal2 antikoerper, COUP(II) antikoerper, NR2F6 antikoerper, couptf2 antikoerper, fc94g11 antikoerper, wu:fc94g11 antikoerper, zgc:77259 antikoerper, ear-2 antikoerper, ear2 antikoerper, erbal2 antikoerper, nr2f6l antikoerper, wu:fc72d04 antikoerper, zgc:77260 antikoerper, nuclear receptor subfamily 2 group F member 6 antikoerper, nuclear receptor subfamily 2, group F, member 6 antikoerper, nuclear receptor subfamily 2, group F, member 6a antikoerper, nuclear receptor subfamily 2 group F member 6 L homeolog antikoerper, nuclear receptor subfamily 2, group F, member 6b antikoerper, NR2F6 antikoerper, Nr2f6 antikoerper, nr2f6a antikoerper, nr2f6.L antikoerper, nr2f6 antikoerper, nr2f6b antikoerper

Hintergrund: Nuclear receptor subfamily 2 group F member 6,NR2F6 (nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity.,EAR2, EAR-2, ERBAL2

Gen-ID: 2063

UniProt: P10588

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism