DUSP6 Antikörper

Produktnummer ABIN7266848

Produktdetails anti-DUSP6 Antikörper

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser DUSP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: DUSP6 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human DUSP6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP6

Target: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Andere Bezeichnung: DUSP6 (DUSP6 Produkte)

Synonyme: HH19 antikoerper, MKP3 antikoerper, PYST1 antikoerper, 1300019I03Rik antikoerper, MKP-3 antikoerper, Mkp3 antikoerper, wu:fd99d09 antikoerper, mkp3 antikoerper, pyst1 antikoerper, DUSP6 antikoerper, dusp6 antikoerper, dual specificity phosphatase 6 antikoerper, dual specificity phosphatase 6 L homeolog antikoerper, Dual specificity protein phosphatase 6 antikoerper, DUSP6 antikoerper, Dusp6 antikoerper, dusp6 antikoerper, dusp6.L antikoerper, dus6 antikoerper

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014],HH19, MKP3, PYST1,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,Kinase,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Neuroscience,Signal Transduction,DUSP6

Molekulargewicht: 42kDa

Gen-ID: 1848

UniProt: Q16828

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades